Section 4.6
Transfusion Reactions

Patient DB received 2 units of group A-positive red cells 2 days ago. Two days later, he developed a fever and appeared jaundiced. His blood type was A positive. A transfusion reaction workup was ordered. There were no clerical errors detected. A post-transfusion specimen was collected and a DAT performed. The DAT was positive with monospecific anti-IgG. The plasma was also hemolyzed. An antibody screen and panel studies revealed the presence of anti-Jk^b (postspecimen). The antibody screen on the pretransfusion specimen was negative.
Which of the following explain the positive DAT?

The donor cells had a positive DAT The donor cells were polyagglutinable The donor cells were likely positive for the Jk^bantigen The recipient cells were likely positive for the Jk^b antigen